Pemphigus vulgaris in a postmenopausal diabetic woman

Autoimmune bullous disorders, such as pemphigus vulgaris (PV), are rare but potentially life-threatening dermatological conditions. This case report presents a 60-year-old postmenopausal woman with PV and a history of type 2 diabetes mellitus (T2DM) who was admitted with skin ulcers and widespread fluid-filled blisters. Investigations confirmed PV through a positive Nikolsky sign, the presence of acantholytic cells, and an IgG fishnet pattern on direct immunofluorescence. Her treatment included corticosteroids, insulin adjustment, and antibiotics. Clinical pharmacist interventions contributed to the identification of adverse drug reactions, IV (intravenous) compatibility, and medication reconciliation. This case emphasizes the importance of individualized multidisciplinary care in autoimmune skin disorders, especially in elderly and comorbid patients.