Heterogeneity of study endpoints in stereotactic body radiation therapy studies for bone metastases: A systematic review.
Considerable heterogeneity in endpoint selection, definitions, and measurement tools across SBRT reflects diverse clinical objectives. Consensus-driven standardisation of endpoints, response criteria, and follow-up schedules is essential to enhance comparability, facilitate evidence synthesis, and support integration of SBRT research findings into clinical practice.
Authors
- Joanne M. van der Velden
- Yvette M. van der Linden (ORCID: https://orcid.org/0000-0002-9003-6124)
- Edward Kai‐Hua Chow (ORCID: https://orcid.org/0000-0002-3075-1898)
- Peter Hoskin (ORCID: https://orcid.org/0000-0001-8323-9567)
- Srinivas Raman (ORCID: https://orcid.org/0000-0001-5688-9628)
- Adrian Wai Chan (ORCID: https://orcid.org/0000-0002-9287-1158)
- Candice Johnstone
- Eva Oldenburger (ORCID: https://orcid.org/0000-0002-2141-8313)
- Saverio Caini (ORCID: https://orcid.org/0000-0002-2262-1102)
- Claudia Cosma (ORCID: https://orcid.org/0009-0000-6958-0275)
- Shing Fung Lee (ORCID: https://orcid.org/0000-0003-4696-9434)
- Caroline Hircock (ORCID: https://orcid.org/0009-0009-2205-6594)
- Pierluigi Bonomo (ORCID: https://orcid.org/0000-0001-8999-5208)
- Samuel Ryu (ORCID: https://orcid.org/0000-0003-1697-0100)
- Agata Rembielak (ORCID: https://orcid.org/0000-0003-2351-7179)
- Charles B. Simone (ORCID: https://orcid.org/0000-0002-0867-3694)
- Sara R. Alcorn (ORCID: https://orcid.org/0000-0003-4620-5047)
- Chiara Doccioli
- Quynh‐Nhu Nguyen (ORCID: https://orcid.org/0000-0001-5274-6291)
- Vassilios Vassiliou (ORCID: https://orcid.org/0000-0003-0659-6848)
- Gustavo Nader Marta (ORCID: https://orcid.org/0000-0002-3298-3684)
- J. Isabelle Choi (ORCID: https://orcid.org/0009-0004-1273-5749)
- Peter A.S. Johnstone
- Henry C Y Wong
- Dirk Rades
Institutions
- Leiden University (NL)
- Hospital Authority (HK)
- Sunnybrook Health Science Centre (CA)
- The University of Texas MD Anderson Cancer Center (US)
- National University of Singapore (SG)
- Universidade de São Paulo (BR)
- University of Toronto (CA)
- Medical College of Wisconsin (US)
- Leiden University Medical Center (NL)
- Stony Brook University Hospital (US)
- Health Sciences Centre (CA)
- University of Manchester (GB)
- University Medical Center Utrecht (NL)
- Moffitt Cancer Center (US)
- National University Cancer Institute, Singapore (SG)
- New York Proton Center (US)
- Mount Vernon Cancer Centre (GB)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Cancer Research UK Manchester Institute (GB)
- The Christie NHS Foundation Trust (GB)
- University of Minnesota Medical Center (US)
- Bank of Cyprus Oncology Center (CY)
- National University Hospital (SG)
- Hospital Sírio-Libanês (BR)
- Piedmont Reference Center for Epidemiology and Cancer Prevention (IT)
- University of Florence (IT)
- University of Lübeck (DE)
- McMaster University (CA)
- KU Leuven (BE)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- Primary Topic
- Management of metastatic bone disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00