Lack of association between loneliness, social isolation and inflammation in people living with HIV aged ≥50 years: Results from the sub-study “No One Alone-Gesida Study”
Inflammation is linked to multiple health conditions. Emerging evidence suggest it may play a role in the association between social isolation - loneliness and health outcomes. People living with HIV (PLWH) exhibit chronic inflammation even with viral suppression, likely due to ongoing immune activation. However, few studies have explored inflammatory biomarker in PLWH experiencing loneliness or social isolation. This study aimed to assess this association in PLWH aged 50 or older.
Authors
- A. López-Lirola (ORCID: https://orcid.org/0009-0002-6530-0103)
- Isabel Sanjoaquín (ORCID: https://orcid.org/0000-0001-5239-7562)
- María Saumoy (ORCID: https://orcid.org/0000-0002-0047-1991)
- Joanna Cano-Smith (ORCID: https://orcid.org/0000-0001-5541-3388)
- Helena Albendín-Iglesias
- Lourdes Romero (ORCID: https://orcid.org/0000-0001-7893-5779)
- Magdalena Muelas‐Fernandez (ORCID: https://orcid.org/0000-0002-4342-4191)
- Inmaculada González‐Cuello
- Alicia González-Baeza (ORCID: https://orcid.org/0000-0003-4351-5947)
- Cristina Tomás‐Jiménez
- Ana Barrios-Blandino
- Herminia Esteban
- Inmaculada Jarrín (ORCID: https://orcid.org/0000-0002-7485-2252)
- Jésica Abadía‐Otero
- Noemí Cabello‐Clotet (ORCID: https://orcid.org/0000-0001-7259-554X)
- Enrique Bernal (ORCID: https://orcid.org/0009-0001-1753-9104)
- Javier de la Torre (ORCID: https://orcid.org/0000-0003-4718-0320)
- José Ramón Blanco (ORCID: https://orcid.org/0000-0002-4268-0150)
- Jordi Puig (ORCID: https://orcid.org/0000-0002-4075-0346)
- Julián Olalla (ORCID: https://orcid.org/0000-0002-8577-3891)
- María José Galindo Puerto (ORCID: https://orcid.org/0000-0002-4911-4071)
- Carmen Hidalgo‐Tenorio (ORCID: https://orcid.org/0000-0002-6394-5728)
- Rafael Torres (ORCID: https://orcid.org/0000-0001-7979-017X)
- Laura Pérez‐Martínez (ORCID: https://orcid.org/0000-0002-1384-024X)
- M. Montero (ORCID: https://orcid.org/0000-0001-5991-6804)
- Dolores Merino-Muñoz
- Antonio Ocampo
- Lucio García‐Fraile (ORCID: https://orcid.org/0000-0002-2512-6107)
- Verónica Pérez‐Esquerdo
- Maria Angeles Fernandes-López
- Eugenia Negredo-Puigmal
Institutions
- Hospital Universitario de Canarias (ES)
- Hospital Universitario La Paz (ES)
- Instituto de Salud Carlos III (ES)
- Bellvitge University Hospital (ES)
- University Hospital Complex Of Vigo (ES)
- Hospital Clínico San Carlos (ES)
- Hospital Costa del Sol (ES)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- Hospital Clínico Universitario de Valencia (ES)
- Hospital de Viladecans (ES)
- Centro de Investigación Biomédica en Red (ES)
- Hospital Universitario Virgen de las Nieves (ES)
- Fundación Seimc-Gesida (ES)
- Hospital Juan Ramón Jiménez (ES)
- Hospital Reina Sofía de Murcia (ES)
- Hospital Clínico Universitario Lozano Blesa (ES)
- Hospital San Pedro (ES)
- Center for Biomedical Research of La Rioja (ES)
- Hospital Vega Baja (ES)
- Hospital Universitario Virgen de la Arrixaca (ES)
- Hospital Universitari Germans Trias i Pujol (ES)
- Hospital Universitario Río Hortega (ES)
- Hospital Universitario Severo Ochoa (ES)
- Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL) (ES)
- Universidad Autónoma de Madrid (ES)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1371/journal.pone.0335949
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00