Large Language Models for Psychiatric Diagnosis Based on Multicenter Real-World Clinical Records: Comparative Study

LLMs-especially GPT-4.0-demonstrate promising capability in supporting psychiatric diagnosis using real-world EHRs. However, diagnostic performance varies by age group and disorder category. LLMs should be regarded as assistive tools rather than replacements for clinical judgment, and further validation is needed before routine clinical implementation.

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Publication Details

Journal
JMIR Medical Informatics
Published
2026-01-13
DOI
https://doi.org/10.2196/77699
Primary Topic
Machine Learning in Healthcare
Type
article
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article

Large Language Models for Psychiatric Diagnosis Based on Multicenter Real-World Clinical Records: Comparative Study

Jia Yu, Huaili Deng, Yunsheng Yang, Jun Feng et al.
JMIR Medical Informatics
Machine Learning in Healthcare
article

Large Language Models for Psychiatric Diagnosis Based on Multicenter Real-World Clinical Records: Comparative Study

Jia Yu, Huaili Deng, Yunsheng Yang, Jun Feng, Jiaquan Liang, Min Sun, Tao Xiao, Guoping Huang, Zebo Long
article en

Abstract

LLMs-especially GPT-4.0-demonstrate promising capability in supporting psychiatric diagnosis using real-world EHRs. However, diagnostic performance varies by age group and disorder category. LLMs should be regarded as assistive tools rather than replacements for clinical judgment, and further validation is needed before routine clinical implementation.

JMIR Medical InformaticsVol. 14
Mianyang Third People's Hospital (CN), Ganzhou People's Hospital (CN), First People's Hospital of Foshan (CN), Taiyuan Iron and Steel Group (China) (CN), Foshan Second People's Hospital (CN), Chongqing Emergency Medical Center (CN), Panzhihua Central Hospital (CN), Third People's Hospital of Huzhou (CN), Changzhou Third People's Hospital (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 99%
Machine Learning in Healthcare
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