Scalable cyberinfrastructure for experimental NMR data
The Network for Advanced NMR (NAN) is a novel distributed resource that connects Nuclear Magnetic Resonance (NMR) facilities via a scalable cyberinfrastructure supporting NMR data harvesting, interactive data management, and the discovery of instruments, methods, and data to enable emerging data standards in biomedicine, chemistry, and material science. Anchored by the first open-access 1.1 GHz instruments in the USA, NAN integrates NMR facilities around a centralized hub for identity management, resource discovery, and access control. The system includes automated data harvesting through the NAN data transport system (NDTS), metadata-rich data archiving, and interactive web-based tools for data and metadata browsing, editing, and publishing, as well as tools for facility and laboratory data management by facility managers and principal investigators. NAN knowledgebases provide vetted, standardized pulse programs, protocols, parameters, and example datasets, along with processed data. Supported by the US National Science Foundation Midscale Research Infrastructure program, NAN helps to democratize access to NMR resources and fosters open, reproducible science.
Authors
- Paulo Pinheiro (ORCID: https://orcid.org/0000-0002-8912-2244)
- John Glushka (ORCID: https://orcid.org/0000-0002-6615-0496)
- Jonathan R. Wedell (ORCID: https://orcid.org/0000-0002-2247-6259)
- Bernd Simon (ORCID: https://orcid.org/0000-0003-0164-5516)
- Alexander L. Paterson (ORCID: https://orcid.org/0000-0002-3069-5910)
- Chad M. Rienstra (ORCID: https://orcid.org/0000-0002-9912-5596)
- Mario Uchimiya (ORCID: https://orcid.org/0000-0003-4802-1428)
- Qi Cheng (ORCID: https://orcid.org/0000-0002-2123-9139)
- John H. Grimes (ORCID: https://orcid.org/0000-0003-1831-174X)
- Harrison Burr
- Katherine A. Henzler‐Wildman (ORCID: https://orcid.org/0000-0002-5295-2121)
- Jeffrey C. Hoch (ORCID: https://orcid.org/0000-0002-9230-2019)
- Michael P. Wilson (ORCID: https://orcid.org/0000-0003-3069-2274)
- Ion I. Moraru (ORCID: https://orcid.org/0000-0002-3746-9676)
- Arthur S. Edison (ORCID: https://orcid.org/0000-0002-5686-2350)
- Alexander Eletsky (ORCID: https://orcid.org/0000-0002-1291-4315)
- Michael R. Gryk
- Mark W. Maciejewski (ORCID: https://orcid.org/0000-0003-1217-1571)
- Alexandra Pozhidaeva (ORCID: https://orcid.org/0000-0001-8602-1790)
- Gerard Weatherby (ORCID: https://orcid.org/0000-0002-0462-4633)
- Yulia Pustovalova (ORCID: https://orcid.org/0000-0003-3024-1764)
- Boden Vanderloop
- Songlin Wang (ORCID: https://orcid.org/0000-0002-7588-7377)
- Abigail E Moore (ORCID: https://orcid.org/0009-0002-5576-2750)
- Laura Morris
- Seenat Thongdee
- Christopher Bontempi (ORCID: https://orcid.org/0009-0007-3783-6484)
Institutions
- University of Wisconsin–Madison (US)
- University of Georgia (US)
- UConn Health (US)
Publication Details
- Journal
- Scientific Data
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1038/s41597-025-06446-y
- Citations
- 1
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Science Foundation