Cavβ dances the two-step with VSD II

JGP study (De Giorgis et al. https://doi.org/10.1084/jgp.202413739) reveals that the auxiliary Cavβ3 subunit regulates the cardiac calcium channel Cav1.2 by modulating the two-step activation of VSD II.

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Publication Details

Journal
The Journal of General Physiology
Published
2025-12-05
DOI
https://doi.org/10.1085/jgp.202513935
Primary Topic
Ion channel regulation and function
Type
article
Field-Weighted Citation Impact
0.00
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article

Cavβ dances the two-step with VSD II

Ben Short
The Journal of General Physiology
Ion channel regulation and function
article

Cavβ dances the two-step with VSD II

Ben Short
article en

Abstract

JGP study (De Giorgis et al. https://doi.org/10.1084/jgp.202413739) reveals that the auxiliary Cavβ3 subunit regulates the cardiac calcium channel Cav1.2 by modulating the two-step activation of VSD II.

The Journal of General PhysiologyVol. 158(1)
Rockefeller University Press (US), Rockefeller University (US)
Openalex Percentile: Top 62%
Ion channel regulation and function
DOIOpen Access PDFOpenAlex
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Cavβ dances the two-step with VSD II — Ben Short · The Journal of General Physiology (2025) | TGRS Research Map | TGRS