Severe Adverse Events Associated with Thiopurine Therapy inInflammatory Bowel Disease: A Retrospective Cohort Study from a Tertiary Center
Thiopurine therapy in inflammatory bowel disease is associated with a notable incidence of severe adverse events, particularly acute pancreatitis and myelotoxicity. No consistent demographic or clinical predictors of toxicity were identified, highlighting the importance of universal monitoring strategies during thiopurine treatment.
Authors
- Luigi Melcarne (ORCID: https://orcid.org/0000-0002-9718-9692)
- María José Ramírez Lázaro
- Luis F. Soto (ORCID: https://orcid.org/0000-0002-6348-6437)
- Albert Villoria Ferrer
- Belén García Sagué
- Luís Enrique Frisancho
- Alberto Guillén (ORCID: https://orcid.org/0000-0001-9918-3238)
- Eduard Brunet‐Mas (ORCID: https://orcid.org/0000-0001-8661-0608)
- Sergio Lario (ORCID: https://orcid.org/0000-0001-9294-1585)
- Xavier Calvet (ORCID: https://orcid.org/0000-0002-4413-4209)
Institutions
- Institute of Research and Innovation Parc Tauli (ES)
Publication Details
- Journal
- Revista Española de Enfermedades Digestivas
- Published
- 2025-01-01
- DOI
- https://doi.org/10.17235/reed.2025.11732/2025
- Citations
- 1
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 1.88