Comparison of long-term efficacy, tolerability and drug survival rates of baricitinib as monotherapy or combination therapy in RA patients: data from a real-world prospective cohort study

In this real-world cohort, baricitinib demonstrated sustained long-term effectiveness, drug survival and an acceptable safety profile. The similar outcomes observed for MONO and COMBO indicate that baricitinib may be used effectively as MONO in patients with RA for whom MTX is not suitable or tolerated.

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Publication Details

Journal
RMD Open
Published
2025-10-01
DOI
https://doi.org/10.1136/rmdopen-2025-006333
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparison of long-term efficacy, tolerability and drug survival rates of baricitinib as monotherapy or combination therapy in RA patients: data from a real-world prospective cohort study

Selahattin Alp Temiz, Axel J. Hueber, Georg Schett, Arnd Kleyer et al.
RMD Open
Rheumatoid Arthritis Research and Therapies
article

Comparison of long-term efficacy, tolerability and drug survival rates of baricitinib as monotherapy or combination therapy in RA patients: data from a real-world prospective cohort study

Selahattin Alp Temiz, Axel J. Hueber, Georg Schett, Arnd Kleyer, Koray Taşçılar, F Hartmann, Sara Bayat
article en

Abstract

In this real-world cohort, baricitinib demonstrated sustained long-term effectiveness, drug survival and an acceptable safety profile. The similar outcomes observed for MONO and COMBO indicate that baricitinib may be used effectively as MONO in patients with RA for whom MTX is not suitable or tolerated.

RMD OpenVol. 11(4)
Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Universitätsklinikum Erlangen (DE), Nuremberg Hospital (DE), Paracelsus Medizinische Privatuniversität (DE), Charité - Universitätsmedizin Berlin (DE)
Deutsche Forschungsgemeinschaft, Leibniz-Gemeinschaft
Openalex Percentile: Top 42%
Rheumatoid Arthritis Research and Therapies
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Comparison of long-term efficacy, tolerability and drug survival rates of baricitinib as monotherapy or combination therapy in RA patients: data from a real-world prospective cohort study — Selahattin Alp Temiz, Axel J. Hueber, et al. · RMD Open (2025) | TGRS Research Map | TGRS