Unraveling the connection between obesity, metabolic syndrome and osteoarthritis risk: a large-observational study
There's a complex interplay between BMI, MetS, and OA. Although MetS mediated a small proportion of the BMI effect, it was not an independent risk factor for OA in the overall population. The impact of MetS on the risk of OA varied by age and BMI levels.
Authors
- Junfei Guo (ORCID: https://orcid.org/0000-0002-5687-3885)
- Xin Xu (ORCID: https://orcid.org/0000-0002-2469-6933)
- Junxiang Wang (ORCID: https://orcid.org/0009-0002-4188-0932)
- Mingyi Yang (ORCID: https://orcid.org/0000-0001-8640-9795)
- Ke Xu (ORCID: https://orcid.org/0000-0003-4364-3770)
- Hui Yu (ORCID: https://orcid.org/0000-0003-3901-7187)
- Zhi Yang
- Jiachen Wang
- Fengjie Guo
- Leixuan Peng (ORCID: https://orcid.org/0009-0003-0610-2497)
- Peng Xu (ORCID: https://orcid.org/0009-0001-4619-4053)
Institutions
- Xi'an Honghui Hospital (CN)
- Xi'an Institute of Optics and Precision Mechanics (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1186/s13098-025-02059-y
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00