Associations between early life adversity and the development of gray matter macrostructure and microstructure

Parental acceptance and trauma resilience are linked to accelerated pace of apparent cortical thinning in youth aged 9-13 years, while household abuse is associated with slower microstructural development, as reflected by smaller longitudinal changes in the T1w/T2w ratio. Threat and deprivation may be distinctly associated with gray matter developmental trajectories in late childhood.

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Publication Details

Journal
Psychological Medicine
Published
2025-01-01
DOI
https://doi.org/10.1017/s0033291725102651
Primary Topic
Child Abuse and Trauma
Type
article
Field-Weighted Citation Impact
0.00

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article

Associations between early life adversity and the development of gray matter macrostructure and microstructure

Lars Tjelta Westlye, Dag Alnæs, Anders Lillevik Thorsen, Andreas Dahl et al.
Psychological Medicine
Child Abuse and Trauma
article

Associations between early life adversity and the development of gray matter macrostructure and microstructure

Lars Tjelta Westlye, Dag Alnæs, Anders Lillevik Thorsen, Andreas Dahl, Olga Therese Ousdal, Florence Friederike Boehmisch
article en

Abstract

Parental acceptance and trauma resilience are linked to accelerated pace of apparent cortical thinning in youth aged 9-13 years, while household abuse is associated with slower microstructural development, as reflected by smaller longitudinal changes in the T1w/T2w ratio. Threat and deprivation may be distinctly associated with gray matter developmental trajectories in late childhood.

Psychological MedicineVol. 55
Oslo University Hospital (NO), University of Oslo (NO), Haukeland University Hospital (NO), Amsterdam Neuroscience (NL), Amsterdam University Medical Centers (NL), University of Bergen (NO)
Trond Mohn stiftelse, European Commission, Universitetet i Bergen, Universitetet i Oslo, Norges Forskningsråd, Helse Sør-Øst RHF
Openalex Percentile: Top 47%
Child Abuse and Trauma
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Associations between early life adversity and the development of gray matter macrostructure and microstructure — Lars Tjelta Westlye, Dag Alnæs, et al. · Psychological Medicine (2025) | TGRS Research Map | TGRS