Brain parenchyma dose-volume predictors of toxicity following Gamma Knife radiosurgery for convexity, parasagittal, and falcine meningiomas.
Our results support adopting brain parenchyma-specific <i>V</i> <sub>12</sub> as a refined predictive dosimetric metric for assessing radiation-induced toxicity in convexity meningiomas. Implementing this refined, parenchyma-specific assessment can enhance safety in SRS, guide individualized treatment decisions, and serve as a practical reference for planning - particularly in eloquent cortical regions where minimizing high-dose brain exposure is critical.
Authors
- Michael Mix (ORCID: https://orcid.org/0000-0002-9106-2519)
- Walter A. Hall
- Mary T Mahoney (ORCID: https://orcid.org/0000-0002-1857-9423)
- Timóteo Almeida (ORCID: https://orcid.org/0000-0002-5426-6264)
- Lawrence S. Chin
- Omar Sey
Institutions
- Fox Chase Cancer Center (US)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 0.00