Machine learning-based identification of pyroptosis-related genes as biomarkers and targets in primary Sjögren's syndrome

This study provides novel insights into the molecular mechanisms of pSD and highlights potential diagnostic biomarkers and therapeutic targets related to pyroptosis. The integration of bioinformatics and machine learning offers a robust framework for understanding the complex interplay between pyroptosis and pSD pathogenesis.

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Publication Details

Journal
Clinical and Experimental Rheumatology
Published
2025-12-18
DOI
https://doi.org/10.55563/clinexprheumatol/zpd69e
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
0.00

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article

Machine learning-based identification of pyroptosis-related genes as biomarkers and targets in primary Sjögren's syndrome

Sheng Gao, Xinyue Liang, Chunyan Hua, Yanggang Hong et al.
Clinical and Experimental Rheumatology
Salivary Gland Disorders and Functions
article

Machine learning-based identification of pyroptosis-related genes as biomarkers and targets in primary Sjögren's syndrome

Sheng Gao, Xinyue Liang, Chunyan Hua, Yanggang Hong, Ting Zhang, Xiaoyang Jiang
article en

Abstract

This study provides novel insights into the molecular mechanisms of pSD and highlights potential diagnostic biomarkers and therapeutic targets related to pyroptosis. The integration of bioinformatics and machine learning offers a robust framework for understanding the complex interplay between pyroptosis and pSD pathogenesis.

Clinical and Experimental RheumatologyVol. 43(12)
Wenzhou Medical University (CN), First Affiliated Hospital of Wenzhou Medical University (CN)
Science and Technology Plan Project of Wenzhou, China, Natural Science Foundation of Zhejiang Province
Openalex Percentile: Top 49%
Salivary Gland Disorders and Functions
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Machine learning-based identification of pyroptosis-related genes as biomarkers and targets in primary Sjögren's syndrome — Sheng Gao, Xinyue Liang, et al. · Clinical and Experimental Rheumatology (2025) | TGRS Research Map | TGRS