High Frequency and Unique Subtypes of Meningioma in Patients with BAP1 Tumor Predisposition Syndrome
This study provides additional evidence that high-grade brain and spinal meningiomas are part of the clinical spectrum of <i>BAP1</i>-TPDS. Craniospinal imaging surveillance in the <i>BAP1</i>-TPDS population should be considered starting around puberty, enabling early detection and management for individuals with <i>BAP1</i>-TPDS.
Authors
- Lindsey Byrne (ORCID: https://orcid.org/0000-0001-7131-5331)
- Joshua D. Palmer (ORCID: https://orcid.org/0000-0003-3311-0129)
- Isabel Gray
- Russell R. Lonser (ORCID: https://orcid.org/0000-0002-8007-707X)
- Rania Sheikh
- Mohamed H. Abdel‐Rahman (ORCID: https://orcid.org/0000-0002-9493-7894)
- Saman Ahmadian (ORCID: https://orcid.org/0000-0002-4133-7895)
- Colleen M. Cebulla (ORCID: https://orcid.org/0000-0002-5636-4968)
- Kelvin Ramsey (ORCID: https://orcid.org/0000-0003-4307-0263)
- Maria Isabel Carlo (ORCID: https://orcid.org/0000-0002-4786-7408)
- Alicia J. Latham (ORCID: https://orcid.org/0000-0002-9758-713X)
- Olivia B. Taylor (ORCID: https://orcid.org/0009-0002-6827-0552)
- Amr S. Soliman (ORCID: https://orcid.org/0000-0002-5528-670X)
- Emma Schreiner
Institutions
- MetroHealth (US)
- Memorial Sloan Kettering Cancer Center (US)
- The Ohio State University Wexner Medical Center (US)
- Neurological Surgery (US)
- The Ohio State University (US)
Publication Details
- Journal
- medRxiv
- Published
- 2025-12-04
- DOI
- https://doi.org/10.64898/2025.12.04.25341363
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Memorial Sloan-Kettering Cancer Center
- National Institutes of Health
- National Center for Advancing Translational Sciences