Dehydroeffusol from Juncus effusus L. exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus in vitro and in vivo
DHE is a promising natural antimicrobial agent with notable activity against S. aureus and MRSA. Its mechanism of action involves membrane disruption and biofilm inhibition, along with preliminary safety in vitro, supporting its potential for further development as an effective antimicrobial agent.
Authors
- X. Grant Chen (ORCID: https://orcid.org/0009-0007-1927-7375)
- Zhiqiang Zhu (ORCID: https://orcid.org/0009-0009-9003-0652)
- Miaolian Wu
- Xiangcheng Fan (ORCID: https://orcid.org/0000-0001-9563-9701)
- Jichun Han (ORCID: https://orcid.org/0000-0002-2650-0519)
- Wei Jin (ORCID: https://orcid.org/0000-0003-2671-1989)
- Xiaojun Xu (ORCID: https://orcid.org/0000-0003-1388-2535)
- Peng Li (ORCID: https://orcid.org/0000-0002-8858-8106)
- Chunyan Dai (ORCID: https://orcid.org/0000-0003-2275-5191)
- Minyang He (ORCID: https://orcid.org/0009-0004-7291-890X)
- Lou S (ORCID: https://orcid.org/0009-0007-9444-6378)
Institutions
- Zhejiang International Studies University (CN)
- Shanxi Agricultural University (CN)
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Tongde Hospital of Zhejiang Province (CN)
Publication Details
- Journal
- International Journal of Medical Microbiology
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1016/j.ijmm.2025.151696
- Citations
- 1
- Primary Topic
- Biological and pharmacological studies of plants
- Type
- article
- Field-Weighted Citation Impact
- 1.39