Molecular subtyping and prognostic evaluation in idiopathic pulmonary fibrosis: a focus on mechanical-related genes
CD24, PPP1R14C, and CC2D2A were identified as prognostic genes associated with MRGs, functioning as markers for molecular subtyping in IPF. These genes may contribute to the pathogenesis of IPF by modulating mechanotransduction processes within epithelial cell subpopulations.
Authors
- Bo Wu (ORCID: https://orcid.org/0000-0003-2027-8651)
- Yansong Guo (ORCID: https://orcid.org/0000-0001-6607-6938)
- Zibin Chen (ORCID: https://orcid.org/0000-0002-7144-1861)
- Yusong Zhi (ORCID: https://orcid.org/0000-0003-2015-3613)
- Jinsheng Hong (ORCID: https://orcid.org/0000-0003-0954-5923)
- Mingwei Zhang (ORCID: https://orcid.org/0000-0002-6769-8357)
- He Huang (ORCID: https://orcid.org/0000-0002-2723-1621)
- Chun Chen (ORCID: https://orcid.org/0000-0003-0404-3094)
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-12-17
- DOI
- https://doi.org/10.1186/s12967-025-07365-7
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00