Comprehensive evaluation of the prevalent insulin resistance indices for pan-cancer incidence and mortality prediction
IR-related indices, especially TyG-WC, are significantly associated with both pan-cancer incidence and cancer-specific mortality. Compared with TyG, TyG-BMI, and TyG-WHtR, TyG-WC demonstrated stronger associations, suggesting its potential utility for stratifying cancer risk and prognosis in clinical and public health settings.
Authors
- Jianye Wang (ORCID: https://orcid.org/0000-0001-7173-566X)
- Shuhang Luo
- Li Ma (ORCID: https://orcid.org/0000-0001-7688-3397)
- Ying Song (ORCID: https://orcid.org/0000-0001-6582-3399)
- Runhua Tang (ORCID: https://orcid.org/0009-0004-0398-7469)
- Shengjie Lin
Institutions
- Xiamen University (CN)
Publication Details
- Journal
- Tropical Medicine and Health
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1186/s41182-025-00884-5
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00