<i>Bifidobacterium longum</i> inhibits <i>Aggregatibacter actinomycetemcomitans–</i> associated gingival epithelial ferroptosis and protects cellular junctions
<i>Aa</i> disrupts gingival epithelial integrity through ferroptosis-mediated oxidative and inflammatory damage. <i>BL</i> effectively suppresses this cascade and protects epithelial junctions, highlighting its therapeutic potential for periodontitis.
Authors
- Di Yan
- Xu Qin (ORCID: https://orcid.org/0000-0002-4381-1538)
- Satoshi Imazato (ORCID: https://orcid.org/0000-0003-3655-4809)
- Xiaolin Sun (ORCID: https://orcid.org/0000-0001-9709-1532)
- Zehui Wang
- Junichi Sasaki (ORCID: https://orcid.org/0000-0002-5190-8524)
- Sun Xiaojuan
- Kun Cao
- Dan Qiu
Institutions
- Ningxia University (CN)
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
- Tongji Hospital (CN)
- Ningxia Center for Diseases Prevention and Control (CN)
- Huazhong University of Science and Technology (CN)
- Institute of Medical Sciences (IN)
- Osaka Dental University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Journal of Oral Microbiology
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1080/20002297.2025.2599607
- Citations
- 2
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 2.93