Solvent-driven sod-ZIF-8 ↔ ZIF-C phase transformation preserves nucleic acid functionality for gene delivery
Solvent plays a critical role in determining the crystalline phase of Zn–imidazole carrier by regulating coordination equilibrium. This reversible phase transformation does not interfere with biocompatibility and gene-delivery performance to cells.
Authors
- Paolo Falcaro (ORCID: https://orcid.org/0000-0001-5935-0409)
- Arpita Poddar (ORCID: https://orcid.org/0000-0001-5806-9711)
- Ravi Shukla (ORCID: https://orcid.org/0000-0002-1537-9637)
- Gary Bryant (ORCID: https://orcid.org/0000-0001-5483-7592)
- Shakil Ahmed Polash (ORCID: https://orcid.org/0000-0003-2987-5444)
- Francesco Carraro (ORCID: https://orcid.org/0000-0001-8485-4676)
Institutions
- Graz University of Technology (AT)
- RMIT University (AU)
Publication Details
- Journal
- RSC Applied Interfaces
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1039/d5lf00306g
- Citations
- 1
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- David and Elaine Potter Foundation
- Australian Government
- RMIT University