Immediate reactions to amyloid PET disclosure in Japanese older adults without dementia
Immediate impact of amyloid disclosure in a Japanese cohort without dementia.Amyloid-positive individuals had higher distress (Impact of Event Scale) after disclosure.Future Time Perspective improved similarly regardless of amyloid positron emission tomography (PET) results.Concerns about Alzheimer's disease slightly rose in PET-positive participants.Female sex and higher baseline depression and anxiety predicted larger distress.
Authors
- Naoki Tomita (ORCID: https://orcid.org/0000-0003-0618-1853)
- Kenji Yoshiyama
- Taizen Nakase (ORCID: https://orcid.org/0000-0002-1796-5859)
- Hisatomo Kowa (ORCID: https://orcid.org/0000-0002-5300-8589)
- Kenichiro Sato (ORCID: https://orcid.org/0000-0003-4351-9526)
- Yoshiki Niimi (ORCID: https://orcid.org/0000-0002-2556-8167)
- Tadashi Tsukamoto (ORCID: https://orcid.org/0000-0002-1782-9187)
- Kengo Ito (ORCID: https://orcid.org/0000-0002-5700-688X)
- Takeshi Ikeuchi
- Kensaku Kasuga (ORCID: https://orcid.org/0000-0002-2178-0769)
- Kenji Ishii (ORCID: https://orcid.org/0000-0002-2928-0072)
- Takeshi Iwatsubo (ORCID: https://orcid.org/0000-0003-1160-8129)
- Ryoko Ihara (ORCID: https://orcid.org/0000-0001-8770-3283)
- Atsushi Iwata (ORCID: https://orcid.org/0000-0001-7308-5314)
- Takashi Kato (ORCID: https://orcid.org/0000-0002-4293-4333)
- Kazushi Suzuki (ORCID: https://orcid.org/0000-0001-7841-7533)
- Michio Senda
Institutions
- Tohoku Institute of Technology (JP)
- Hyogo University of Health Sciences (JP)
- Osaka Gakuin University (JP)
- National Center of Neurology and Psychiatry (JP)
- University of Tokyo Hospital (JP)
- Tokyo Metropolitan Institute of Gerontology (JP)
- National Center for Geriatrics and Gerontology (JP)
- Kobe City Medical Center General Hospital (JP)
- National Defense Medical College (JP)
- Kobe University (JP)
- Niigata University (JP)
- The University of Tokyo (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Alzheimer s & Dementia Translational Research & Clinical Interventions
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/trc2.70167
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Japan Agency for Medical Research and Development