Progression of Neuroinflammation Is Associated With Clinical Prognosis of Patients Undergoing Intravenous Thrombolysis
The increase in GFAP levels over the first 24 hours after IVT is independently associated with clinical outcomes, with higher baseline peripheral inflammation correlating with greater GFAP elevation during that period.
Authors
- Yongfei Jiang (ORCID: https://orcid.org/0000-0003-4910-3898)
- Reziya Abuduxukuer
- Yang Qu (ORCID: https://orcid.org/0000-0001-8598-3517)
- Xuefeng Hu (ORCID: https://orcid.org/0000-0001-9683-3506)
- Xin Sun (ORCID: https://orcid.org/0009-0008-7483-7766)
- Zhen‐Ni Guo (ORCID: https://orcid.org/0000-0002-8922-3862)
- Yi Yang (ORCID: https://orcid.org/0000-0002-9729-8522)
- Dan Xu (ORCID: https://orcid.org/0000-0002-3457-6695)
- Ligang Jiang
- Shanjun Tan (ORCID: https://orcid.org/0000-0002-8624-1192)
- Zhi-Mei Yuan
- Li-Chong Yang
- Feng-Lan Zhao (ORCID: https://orcid.org/0000-0003-0987-1702)
- Yu Zhang (ORCID: https://orcid.org/0009-0006-6432-9982)
- Chao Li (ORCID: https://orcid.org/0000-0002-4417-1739)
- Peng Zhang (ORCID: https://orcid.org/0000-0001-5536-0255)
- Huimin Li (ORCID: https://orcid.org/0000-0003-3931-5598)
- Jinfeng Li (ORCID: https://orcid.org/0009-0005-8439-9665)
- Yuping Zheng (ORCID: https://orcid.org/0009-0005-0973-2480)
- Xiaojia Wang (ORCID: https://orcid.org/0000-0002-7005-0842)
- Lijuan Wang (ORCID: https://orcid.org/0000-0002-6120-6200)
- Yingbin Qi
- Chao Han (ORCID: https://orcid.org/0009-0007-2835-8281)
- Hang Jin (ORCID: https://orcid.org/0000-0003-0300-5918)
- Lijie Guo (ORCID: https://orcid.org/0000-0003-2566-8704)
- Lili He
- Xiaoming Zou (ORCID: https://orcid.org/0000-0003-4569-9823)
- Tian Zhou (ORCID: https://orcid.org/0009-0004-9704-3740)
- Xu Han (ORCID: https://orcid.org/0000-0002-3963-4348)
Institutions
- Xuzhou Medical College (CN)
- Jilin University (CN)
- Stroke Association (GB)
- People 's Hospital of Jilin Province (CN)
- Integrated Chinese Medicine (China) (HK)
- Bethune Second Hospital (CN)
- Jilin City Central Hospital (CN)
- Changchun Obstetrics and Gynecology Hospital (CN)
- Shengli Oilfield Central Hospital (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- First Hospital of Jilin University (CN)
- Songjiang District Central Hospital (CN)
- Changchun 208 Hospital (CN)
- Jilin Medical University (CN)
- Second Affiliated Hospital of Jilin University (CN)
- Xuzhou No.1 People's Hospital (CN)
- Brain Hospital of Jilin (CN)
- Guhua Hospital (CN)
Publication Details
- Journal
- Stroke
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1161/strokeaha.125.053004
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00