Macular vessel density as a novel biomarker for glaucoma diagnosis in highly myopic eyes: a multicenter study
Macular SVD in the inferior perifoveal sector demonstrated superior diagnostic performance to peripapillary vessel density in highly myopic glaucoma, while GCCT showed comparable global discrimination. Combined OCTA and OCT imaging significantly enhance diagnostic accuracy and functional correlation, offering critical clinical utility for glaucoma diagnosis and monitoring in highly myopic patients.
Authors
- Sheng Ye (ORCID: https://orcid.org/0000-0001-7857-9794)
- Zhoumo Zeng (ORCID: https://orcid.org/0000-0001-8220-598X)
- Xi Chen (ORCID: https://orcid.org/0000-0003-2675-695X)
- Qin Chen (ORCID: https://orcid.org/0000-0002-0526-2005)
- Qingwei Meng
- Hua Zhong (ORCID: https://orcid.org/0000-0001-9604-4523)
- Jing Liu (ORCID: https://orcid.org/0000-0002-3255-3019)
Institutions
- Kunming Medical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1186/s12967-025-07594-w
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Kunming Medical University
- Nanjing Medical University