PLAUR, C3, and EMP3 coordinate tumor progression and immune evasion in clear cell renal cell carcinoma
PLAUR, C3, and EMP3 promote ccRCC progression and immune evasion, with PLAUR acting as the dominant driver. Targeting PLAUR may provide a promising strategy to enhance anti-tumor immunity in ccRCC.
Authors
- Shuangfeng Zi (ORCID: https://orcid.org/0009-0004-0768-0077)
- Lihua Dong (ORCID: https://orcid.org/0000-0002-4039-963X)
- Zengwei Feng (ORCID: https://orcid.org/0000-0002-8222-5427)
Institutions
- Kunming University of Science and Technology (CN)
- First People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1007/s12672-025-04292-3
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00