Ginsenoside Rg1 promotes skin flap survival by alleviating mitochondrial oxidative stress and apoptosis via the JNK/ERK/p38 pathway
Ginsenoside Rg1 regulates the JNK/ERK/p38 signaling pathway, mitigates mitochondrial oxidative stress and suppresses apoptosis, establishing a novel therapeutic target for flap necrosis prevention.
Authors
- Jiapeng Deng (ORCID: https://orcid.org/0000-0002-0332-9296)
- Kaitao Wang
- Wu Song (ORCID: https://orcid.org/0000-0002-0542-7332)
- H. Y. Pan
- Jialong Yang (ORCID: https://orcid.org/0000-0002-3112-5012)
- Dingsheng Lin (ORCID: https://orcid.org/0000-0003-2021-0155)
- An Wang (ORCID: https://orcid.org/0000-0002-7027-6614)
- Ping Xu (ORCID: https://orcid.org/0000-0003-4166-042X)
Institutions
- Wenzhou Medical University (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1016/j.jgr.2025.100934
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00