Identification of NK cell marker genes based on single-cell sequencing to establish a prognostic signature in breast cancer
In summary, we constructed a prognostic signature characterized by strong predictive performance, which has elucidated the critical role of NK cells in the pathogenesis of breast cancer. Furthermore, this model offers a predictive index and identifies a novel therapeutic target for the advancement of immunotherapeutic strategies in the clinical management of breast cancer patients.
Authors
- Xiangmei He
- Juliang Zhang (ORCID: https://orcid.org/0000-0001-9834-6349)
- Donghui Wang (ORCID: https://orcid.org/0000-0003-3478-1581)
- Lan Hou (ORCID: https://orcid.org/0000-0002-6148-8180)
- Jiawei Zhang (ORCID: https://orcid.org/0000-0001-5127-9142)
Institutions
- Nanchang University (CN)
- Xijing Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1007/s12672-025-03647-0
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00