Enhancing radial strength and expansion uniformity of iron-based vascular scaffolds: a numerical and experimental investigation on topological optimization
<i>In vitro</i> expansion experiments confirmed substantially improved expansion homogeneity, while its radial strength (260.07±4.68 kPa) exceeded that of magnesium/polymer scaffolds, achieving parity with CoCr alloy stents. Enhanced expansion homogeneity mitigates coating fracture risks while maintaining clinically sufficient support.
Authors
- Luyao Tang (ORCID: https://orcid.org/0000-0002-5459-695X)
- Qin Li (ORCID: https://orcid.org/0000-0001-7364-6900)
- Wenchao Fu
- Jian Song (ORCID: https://orcid.org/0000-0002-2608-2468)
- Jia Qiu (ORCID: https://orcid.org/0000-0003-1023-3214)
- Deyuan Zhang (ORCID: https://orcid.org/0000-0001-9401-5032)
- Shuhan Wang (ORCID: https://orcid.org/0000-0002-6562-3351)
Institutions
- Sun Yat-sen University (CN)
- Lifetech Scientific (China) (CN)
- Shenzhen Institute for Drug Control (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-12-19
- DOI
- https://doi.org/10.3389/fbioe.2025.1736027
- Primary Topic
- Magnesium Alloys: Properties and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00