A method for measuring first glymphatic influx of a cerebrospinal fluid tracer in the human brain
Segmented regression was found feasible to quantify the time to first glymphatic enrichment, i.e., increase in the normalized MRI T1 signal. Moreover, the method seems reasonable to differentiate first glymphatic influx between the cohorts.
Authors
- Geir Ringstad (ORCID: https://orcid.org/0000-0003-0919-4510)
- Per Kristian Eide (ORCID: https://orcid.org/0000-0001-6881-9280)
- Are Hugo Pripp (ORCID: https://orcid.org/0000-0002-1678-7309)
- Lars Magnus Valnes (ORCID: https://orcid.org/0000-0001-9283-5563)
Institutions
- Oslo University Hospital (NO)
- OsloMet – Oslo Metropolitan University (NO)
- University of Oslo (NO)
- Sørlandet Hospital Arendal (NO)
- Universidad Metropolitana (PR)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-12-19
- DOI
- https://doi.org/10.3389/fnins.2025.1703748
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Stiftelsen Kristian Gerhard Jebsen