Effects of Electroacupuncture at <scp>ST</scp> 36 on Visceral Pain and Inflammatory Markers in <scp>IBS</scp> Rats
EA at ST36 produced significant analgesic and anti-inflammatory effects in IBS model rats. Visceral hypersensitivity was blunted and colonic inflammatory biomarkers (cytokines, TRPV1, NF-κB) were suppressed by EA, suggesting that EA at ST36 modulates neuro-immune pathways to relieve IBS-related pain. These findings support the therapeutic potential of ST36-targeted electroacupuncture for managing IBS visceral pain via inflammatory mechanism attenuation.
Authors
- Xiaohua Yang (ORCID: https://orcid.org/0009-0001-4416-9962)
- Fei Dai (ORCID: https://orcid.org/0009-0003-9309-5992)
- Yuming Hao
- Y F Liu
- Kai Cheng (ORCID: https://orcid.org/0000-0001-6303-015X)
- Qiang Tu (ORCID: https://orcid.org/0000-0002-8602-3347)
- Xiaomei Wang (ORCID: https://orcid.org/0000-0001-7411-9184)
Institutions
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- First Hospital of Jiaxing (CN)
Publication Details
- Journal
- Neurogastroenterology & Motility
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1111/nmo.70195
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00