Evaluating the combined impact of amphotericin B and posaconazole on the germination of a rare Rhizopus homothallicus isolate responsible for COVID-19 associated mucormycosis
Combination therapy reduced the AMB dose without loss of efficacy, suggesting a synergistic effect against R. homothallicus. These results may support this alternative strategy to mitigate the side effects of AMB.
Authors
- Atul Kumar Tiwari (ORCID: https://orcid.org/0000-0003-3188-3566)
- Roger J. Narayan (ORCID: https://orcid.org/0000-0002-4876-9869)
- Munesh Kumar Gupta (ORCID: https://orcid.org/0000-0002-2107-1727)
- Mohit Bhatia (ORCID: https://orcid.org/0009-0001-4962-6456)
- Suchita Gautam
- Ragini Tilak (ORCID: https://orcid.org/0000-0001-9865-9353)
- Aishwarya Nikhil (ORCID: https://orcid.org/0009-0000-0399-8505)
Institutions
- North Carolina State University (US)
- UNC/NCSU Joint Department of Biomedical Engineering (US)
- Indian Institute of Technology BHU (IN)
- Banaras Hindu University (IN)
Publication Details
- Journal
- Revista Iberoamericana de Micología
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1016/j.riam.2025.10.003
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00