Efficacy of botulinum toxin type A in myogenic temporomandibulardisorders: a single arm, prospective, pilot study
BoNT-A showed promising results in reducing pain and improving function in patients with myofascial pain in Temporomandibular Disorders (M-TMDs). However, the single-arm design, small sample size, and short follow-up limit causal inference and external validity. These findings should be interpreted as preliminary.<b>Clinical Trial Registration</b>: Clinicaltrials.gov, identifier NCT05651256.
Authors
- Nansi López-Valverde (ORCID: https://orcid.org/0000-0002-4168-3085)
- Bruno Macedo de Sousa (ORCID: https://orcid.org/0000-0001-7833-4607)
- Carolina Ferreira (ORCID: https://orcid.org/0000-0002-0051-9721)
- Antonio López‐Valverde (ORCID: https://orcid.org/0000-0003-4784-1870)
- André Almeida (ORCID: https://orcid.org/0000-0002-4389-2825)
- José Antonio Blanco Rueda (ORCID: https://orcid.org/0000-0003-2909-0321)
Institutions
- Universidad de Salamanca (ES)
- Escola Superior de Saúde Egas Moniz (PT)
- Instituto de Investigación Biomédica de Salamanca (ES)
- University of Coimbra (PT)
Publication Details
- Journal
- Frontiers in Rehabilitation Sciences
- Published
- 2025-12-19
- DOI
- https://doi.org/10.3389/fresc.2025.1737706
- Primary Topic
- Temporomandibular Joint Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00