Elevated blood levels of liver-expressed antimicrobial peptide 2 in patients with insulinoma and its expression in insulinomas
Serum LEAP2 levels are elevated in insulinoma and correlate with hyperinsulinemia and BMI. LEAP2 is expressed in insulinoma tissue, suggesting a potential role in the metabolic profile of these patients.
Authors
- Anli Tong (ORCID: https://orcid.org/0000-0002-1418-1012)
- Yunlu Feng (ORCID: https://orcid.org/0000-0002-2761-100X)
- Yuan‐Jia Chen
- Ling Zhong
- Dachun Zhao (ORCID: https://orcid.org/0000-0003-2203-9259)
- Yinjie Gao (ORCID: https://orcid.org/0000-0001-6034-1999)
- Taiping Zhang (ORCID: https://orcid.org/0000-0003-1689-6908)
- Jialei Zhang (ORCID: https://orcid.org/0000-0002-4556-8500)
- Yu-Li Song
- Ming Li
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-12-19
- DOI
- https://doi.org/10.3389/fendo.2025.1685806
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chinese Academy of Medical Sciences
- Peking Union Medical College Hospital