Performance of the APCS- <i>SDC2</i> Score Based on a Fecal <i>SDC2</i> Methylation Assay for the Detection of Colorectal Polyps: A Multicenter Diagnostic Study
Accumulating evidence indicates that fecal syndecan-2 (SDC2) methylation is a promising biomarker for early detection of colorectal cancer. This study aimed to investigate the diagnostic efficacy of fecal SDC2 methylation testing for adenomas and evaluate the risk stratification efficacy of the Asia-Pacific Colorectal Screening Scoring (APCS) combined with SDC2 methylation status.
Authors
- Haibiao Bao
- Huang Liang (ORCID: https://orcid.org/0000-0002-9607-7939)
- Yuan Chen (ORCID: https://orcid.org/0009-0006-2917-1323)
- Ming Cheng (ORCID: https://orcid.org/0000-0001-7098-6790)
- Bin Lü (ORCID: https://orcid.org/0000-0002-6247-571X)
- Jing Zhao (ORCID: https://orcid.org/0009-0002-7416-094X)
- Xu Li (ORCID: https://orcid.org/0000-0002-7893-0457)
- Yue Hu (ORCID: https://orcid.org/0000-0001-5346-0164)
- Ting Ye (ORCID: https://orcid.org/0000-0002-5704-400X)
- Xiaoliang Jin (ORCID: https://orcid.org/0000-0001-8768-3534)
- Haifeng Jin (ORCID: https://orcid.org/0000-0002-1215-554X)
Publication Details
- Journal
- Cancer Screening and Prevention
- Published
- 2025-12-19
- DOI
- https://doi.org/10.14218/csp.2025.00025
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00