Myocardial fibrosis and its relationship with ventricular arrhythmias and reduced ventricular systolic function in young and veteran endurance athletes

Middle-aged athletes more frequently exhibit myocardial fibrosis than young athletes and middle-aged non-athletes. Non-hinge-point fibrosis is present in up to one-fifth of middle-aged athletes and predictive of a higher burden of both unifocal and multifocal ventricular ectopy. Reduced systolic function is more prevalent in athletes and not predicted by fibrosis.

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Publication Details

Journal
European Journal of Preventive Cardiology
Published
2025-11-06
DOI
https://doi.org/10.1093/eurjpc/zwaf715
Primary Topic
Cardiovascular Effects of Exercise
Type
article
Field-Weighted Citation Impact
0.00
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article

Myocardial fibrosis and its relationship with ventricular arrhythmias and reduced ventricular systolic function in young and veteran endurance athletes

Kaatje Goetschalckx, Luke Spencer, Hielko Miljoen, Tim Van Puyvelde et al.
European Journal of Preventive Cardiology
Cardiovascular Effects of Exercise
article

Myocardial fibrosis and its relationship with ventricular arrhythmias and reduced ventricular systolic function in young and veteran endurance athletes

Kaatje Goetschalckx, Luke Spencer, Hielko Miljoen, Tim Van Puyvelde, Bert Vandenberk, Jarne De Paepe, Olivier Ghekiere, Hein Heidbüchel, Kristof Lefebvre, André La Gerche, Ruben De Bosscher, Youri Bekhuis, Adrian D. Elliott, Maria Brosnan, Isabel Witvrouwen, Dominique Hansen, Elizabeth Davida Paratz, Tom Dresselaers, Dorien Vermeulen, Peter Sinnaeve, Bernard P. Paelinck, Prashanthan Sanders, Boris Delpire, Mathias Claeys, Kristel Janssens, Daisy Thijs, Lieven Herbots, Paolo D’Ambrosio, Sofie Van Soest, Jonathan M. Kalman, Peter Vanvoorden, Peter Hespel, Diane Fatkin, Jan Bogaert, Guido Claessen, Kasper Favere, Caroline M. Van De Heyning, S. Rowe, Rik Willems, David L. Prior, Bert O. Eijnde, Tomas Robyns, Peter M. Kistler, Christophe Dausin, Amy M Mitchell, Piet Claus, Steven Dymarkowski, Rik Pauwels
article en

Abstract

Middle-aged athletes more frequently exhibit myocardial fibrosis than young athletes and middle-aged non-athletes. Non-hinge-point fibrosis is present in up to one-fifth of middle-aged athletes and predictive of a higher burden of both unifocal and multifocal ventricular ectopy. Reduced systolic function is more prevalent in athletes and not predicted by fibrosis.

European Journal of Preventive Cardiology
Royal Adelaide Hospital (AU), The Royal Melbourne Hospital (AU), Baker Heart and Diabetes Institute (AU), University of Antwerp (BE), The University of Melbourne (AU), Victor Chang Cardiac Research Institute (AU), The Heart Research Institute (AU), The Alfred Hospital (AU), Cardiovascular Institute Hospital (JP), UNSW Sydney (AU), St Vincent's Hospital Sydney (AU), Jessa Hospital (BE), Antwerp University Hospital (BE), Province of Antwerp (BE), Hartcentrum Hasselt (BE), Australian Centre for Heart Health (AU), Monash University (AU), The University of Adelaide (AU), Hasselt University (BE), KU Leuven (BE)
Openalex Percentile: Top 42%
Cardiovascular Effects of Exercise
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