Evaluation of Residual Patterns of Cyantraniliprole, Ethaboxam, Fludioxonil, and Metalaxyl in Jujube (Ziziphus jujuba Mill.)

This study was performed to evaluate the residual patterns of cyantraniliprole, ethaboxam, fludioxonil, and metalaxyl in jujube (Ziziphus jujuba Mill.) in field trials.Jujubes were collected at different pre-harvest days and subjected to modified QuEChERS sample preparation methods after dried or not.Jujube samples were extracted with organic solvents for pesticide residue analysis using liquid chromatography-tandem mass spectrometry (LC/MS/MS).Residual concentrations in fresh jujube ranged from 0.02 to 0.12 mg/kg for cyantraniliprole, including metabolites, ranged from 0.22 to 1.01 mg/kg for ethaboxam, ranged from 0.05 to 0.53 mg/kg for fludioxonil, and ranged from 0.16 to 2.26 mg/kg for metalaxyl.The biological half-lives for cyantraniliprole, ethaboxam, fludioxonil, and metalaxyl were 8.6, 10.7, 7.1, and 6.3 days, respectively.Based on residue data, the Pre Harvests Intervals (PHIs) were suggested as follows: cyantraniliprole, 2 times applications 7 days before harvest (DBH); ethaboxam, 3 times applications 14 DBH; fludioxonil, 2 times applications 21 DBH; metalaxyl, 3 times applications 7 DBH.The risk assessment based on the percentage of acceptable daily intake indicated that all pesticides were found to be at safe levels, each below 0.05%.These findings provide foundational data for the registration of the tested pesticides in jujube, contributing to pesticide safety and the establishment of effective pest management strategies in jujube cultivation.