Three-dimensional imaging of mechanical contrast in human breast using dynamic optical coherence tomography

We demonstrate a novel approach to generate contrast between healthy and cancerous human breast tissue based on changes in mechanical properties using dynamic optical coherence tomography, validated using co-registered histology.

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Published
2025-12-18
DOI
https://doi.org/10.1117/12.3098535
Primary Topic
Optical Coherence Tomography Applications
Type
article
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article

Three-dimensional imaging of mechanical contrast in human breast using dynamic optical coherence tomography

Ken Y. Foo, Mireille Hardie, Anmol Rijhumal, Matt S. Hepburn et al.
Optical Coherence Tomography Applications
article

Three-dimensional imaging of mechanical contrast in human breast using dynamic optical coherence tomography

Ken Y. Foo, Mireille Hardie, Anmol Rijhumal, Matt S. Hepburn, Laura Gale, Seweryn Morawiec, Christobel Saunders, Brendan F. Kennedy, Marta K. Skrok, Szymon Tamborski, Renate Zilkens, Saud Hamza, Joel A. Bellesini
article en

Abstract

We demonstrate a novel approach to generate contrast between healthy and cancerous human breast tissue based on changes in mechanical properties using dynamic optical coherence tomography, validated using co-registered histology.

The University of Melbourne (AU), The University of Western Australia (AU), Harry Perkins Institute of Medical Research (AU), Fiona Stanley Hospital (AU), Nicolaus Copernicus University (PL)
Openalex Percentile: Top 60%
Optical Coherence Tomography Applications
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