Advances in <scp>3D</scp> Printing for Personalized Pharmaceuticals

ABSTRACT The review examines the present state of 3D‐printed pharmaceuticals by analyzing preclinical applications and recent developments in printing technologies and printable formulations for clinical translation. Notably, the computer‐aided design‐based revolutionizing manufacturing process known as 3D printing enables layer‐by‐layer construction of solid objects which produces benefits that conventional pharmaceutical manufacturing methods lack including customized dosages and on‐demand production and complex drug delivery system creation. Among these, 3D printing technologies of SLS and FDM and Semi‐Solid Extrusion along with stereolithography have become essential for developing advanced materials and structures that serve multiple fields through their ability to create complex drug delivery systems with customized release profiles and sublingual and fast‐dissolving formulations. Despite these advances, the extensive potential of 3D printing in pharmaceutical manufacturing remains restricted by material compatibility issues and structural consistency problems and cost‐efficiency limitations and regulatory challenges. Consequently, current research activities continue to focus on solving these manufacturing challenges and improving current technologies and increasing the drug production capabilities of 3D printing. This review offers a comprehensive review of 3D printing systems and their benefits and drawbacks in pharmaceutical applications and future directions for this technology to be used by researchers and industry professionals to develop patient‐centered healthcare solutions.