Minimal Residual Disease Detection in Peripheral Blood of Patients With High-Risk Neuroblastoma Correlates With Outcome in the International GPOH-DCOG Prospective Validation Study
PB infiltration is associated with EFS and OS at diagnosis; it is also significantly associated with survival outcomes of patients with ≥10% BM infiltration at diagnosis. During follow-up, neuroblastoma mRNA detection in PB can be of added value, when BM analysis is not possible.
Authors
- Lieke M. J. van Zogchel (ORCID: https://orcid.org/0000-0003-3557-7195)
- Marta Fiocco (ORCID: https://orcid.org/0000-0001-5588-0277)
- Janine Stutterheim (ORCID: https://orcid.org/0000-0002-9828-0834)
- Ahmad Javadi
- Max M. van Noesel (ORCID: https://orcid.org/0000-0003-0503-5838)
- Esther M. van Wezel
- Nina U. Gelineau (ORCID: https://orcid.org/0009-0000-0348-8724)
- C. Ellen van der Schoot (ORCID: https://orcid.org/0000-0002-8065-3540)
- Frank Berthold (ORCID: https://orcid.org/0000-0002-7613-1723)
- Godelieve A.M. Tytgat (ORCID: https://orcid.org/0000-0003-4452-0748)
- Barbara Hero (ORCID: https://orcid.org/0000-0003-4129-890X)
- Thorsten Simon (ORCID: https://orcid.org/0000-0002-3425-8451)
- Boris De Carolis
- Lily Zappeij‐Kannegieter (ORCID: https://orcid.org/0000-0002-5493-5149)
- Roswitha Schumacher‐Kuckelkorn
Institutions
- Leiden University (NL)
- Utrecht University (NL)
- Leiden University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Sanquin (NL)
- Princess Máxima Center (NL)
- University Hospital Cologne (DE)
Publication Details
- Journal
- JCO Precision Oncology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1200/po-25-00235
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00