Integrated Genetic Information of Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Traits Improves Hepatocellular Carcinoma Risk Stratification and Screening
The MASLD-related metaPRS supports effective population risk stratification and enables a layered HCC screening strategy combining genetic risk profiling with targeted clinical assessment.
Authors
- Zhenqiu Liu (ORCID: https://orcid.org/0000-0002-5244-6894)
- Xingdong Chen (ORCID: https://orcid.org/0009-0006-6096-2633)
- Huangbo Yuan (ORCID: https://orcid.org/0000-0002-7065-2974)
- Tiejun Zhang (ORCID: https://orcid.org/0000-0002-5187-7393)
- Tao Wu (ORCID: https://orcid.org/0000-0002-5750-909X)
- Mingyi Du (ORCID: https://orcid.org/0009-0009-3921-8844)
Institutions
- Fudan University (CN)
- Pudong Medical Center (CN)
- Huashan Hospital (CN)
- Taizhou University (CN)
Publication Details
- Journal
- JCO Precision Oncology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1200/po-25-00638
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35