Progression of Presumed Pentosan Polysulfate Sodium Maculopathy After Drug Cessation

This case report discusses presumed progression of maculopathy secondary to pentosan polysulfate sodium prescribed for daily use over a period of 4 years in a patient with a history of interstitial cystitis.

Authors

Kimberly E. Stepien (ORCID: https://orcid.org/0000-0002-4498-6495)
Hyun Sue Kim (ORCID: https://orcid.org/0000-0002-4727-6499)
Elaine Botros

Publication Details

Journal: JAMA Ophthalmology
Published: 2025-12-18
DOI: https://doi.org/10.1001/jamaophthalmol.2025.3642
Primary Topic: Urinary Bladder and Prostate Research
Type: article
Field-Weighted Citation Impact: 0.00

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article

Progression of Presumed Pentosan Polysulfate Sodium Maculopathy After Drug Cessation

Kimberly E. Stepien, Hyun Sue Kim, Elaine Botros

Dec 18, 2025

JAMA Ophthalmology

Urinary Bladder and Prostate Research

article

Progression of Presumed Pentosan Polysulfate Sodium Maculopathy After Drug Cessation

Kimberly E. Stepien, Hyun Sue Kim, Elaine Botros

December 18, 2025article en

Abstract

JAMA OphthalmologyVol. 143(12)

Openalex Percentile: Top 44%

Urinary Bladder and Prostate Research

DOI Source OpenAlex

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