Biomarkers of Glycolysis and the Tricarboxylic Acid Cycle in Youth with and without Obesity

The metabolomic analysis revealed distinct characteristics between adolescents with and without obesity, thus demonstrating lower rates of aerobic glucose utilization in youth with obesity, which may contribute to the development of insulin resistance, type 2 diabetes, and cardiovascular disease.

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Publication Details

Journal
Hormone Research in Paediatrics
Published
2025-12-18
DOI
https://doi.org/10.1159/000548624
Primary Topic
Metabolomics and Mass Spectrometry Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Biomarkers of Glycolysis and the Tricarboxylic Acid Cycle in Youth with and without Obesity

Emiliano Barbieri, Zhongyao Li, Stephanie Samuels, Nicola Santoro et al.
Hormone Research in Paediatrics
Metabolomics and Mass Spectrometry Studies
article

Biomarkers of Glycolysis and the Tricarboxylic Acid Cycle in Youth with and without Obesity

Emiliano Barbieri, Zhongyao Li, Stephanie Samuels, Nicola Santoro, Michelle Van Name, Brittany Galuppo, Giuseppina Rosaria Umano, Janice J. Hwang, Guo‐Jun Kang, Ermena Refugjati
article en

Abstract

The metabolomic analysis revealed distinct characteristics between adolescents with and without obesity, thus demonstrating lower rates of aerobic glucose utilization in youth with obesity, which may contribute to the development of insulin resistance, type 2 diabetes, and cardiovascular disease.

Hormone Research in Paediatrics
University of North Carolina at Chapel Hill (US), Tufts University (US), University of Molise (IT), Yale University (US), University of Campania "Luigi Vanvitelli" (IT), University of Naples Federico II (IT)
Openalex Percentile: Top 63%
Metabolomics and Mass Spectrometry Studies
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