Accuracy and clinical impact of MRI in early-stage cervical cancer after cervical conization, a retrospective study
Question MRI evaluation of residual tumor after cervical conization in early-stage cervical cancer is critical to optimize surgical planning noninvasively and avoid overtreatment. Findings MRI correctly identified residual disease with high specificity (90.9%) and moderate sensitivity (66%); contrast enhancement did not significantly improve diagnostic accuracy. Clinical relevance MRI, particularly non-contrast protocols, reliably excludes post-conization residual disease and aids in selecting appropriate surgical treatment, reducing overtreatment in early-stage cervical cancer.
Authors
- Benedetta Gui (ORCID: https://orcid.org/0000-0002-5130-2100)
- Miriam Dolciami (ORCID: https://orcid.org/0000-0002-8322-8435)
- Luca Russo (ORCID: https://orcid.org/0000-0002-0495-7462)
- Marco Petrillo (ORCID: https://orcid.org/0000-0003-0306-4328)
- Francesco Fanfani (ORCID: https://orcid.org/0000-0003-1991-7284)
- Evis Sala (ORCID: https://orcid.org/0000-0002-5518-9360)
- Antonio Napoletano
- Nicolò Bizzarri (ORCID: https://orcid.org/0000-0002-1727-904X)
- Giulia Scaglione (ORCID: https://orcid.org/0000-0002-9060-3854)
- Diana Giannarelli (ORCID: https://orcid.org/0000-0002-6085-1195)
- Andrea Amerighi
- Massimo Criscione (ORCID: https://orcid.org/0000-0002-1627-2444)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Sassari (IT)
- Agostino Gemelli University Polyclinic (IT)
- University of the Sacred Heart (JP)
Publication Details
- Journal
- European Radiology
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1007/s00330-025-12178-9
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00