Overexpression of PTPRCAP inhibits biological function of lung adenocarcinoma through apoptosis pathway
PTPRCAP is downregulated in LUAD and acts as a tumor suppressor by promoting apoptosis and inhibiting proliferation, migration, and invasion. These findings suggest PTPRCAP as a potential therapeutic target for LUAD.
Authors
- Yuting Yang (ORCID: https://orcid.org/0009-0003-5307-2091)
- Zongying Liang
- Yingjie Jiang
- Jingtao Huang
- Xiaoli Han (ORCID: https://orcid.org/0000-0002-4297-8934)
- Guo‐ping Sun
- Baoshan Zhao (ORCID: https://orcid.org/0000-0003-1583-3083)
Institutions
- Hospital of Hebei Province (CN)
- Chengde Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1371/journal.pone.0337223
- Primary Topic
- Protein Tyrosine Phosphatases
- Type
- article
- Field-Weighted Citation Impact
- 0.00