Frequency of Nonspecific Optic Nerve Sheath Enhancement on Magnetic Resonance Imaging

ONSE can be seen in a small proportion of patients without optic nerve pathology and may be missed in subtle disease, emphasizing the importance of clinical correlation. Higher field strength MRI may improve sensitivity for detecting pathologic ONSE but can have false positives. These findings underscore the need for cautious interpretation of ONSE, particularly in asymptomatic individuals or in the context of high-resolution imaging.

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Publication Details

Journal
Journal of Neuro-Ophthalmology
Published
2025-12-18
DOI
https://doi.org/10.1097/wno.0000000000002426
Primary Topic
Cerebral Venous Sinus Thrombosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Frequency of Nonspecific Optic Nerve Sheath Enhancement on Magnetic Resonance Imaging

Ajay A. Madhavan, Mary V. Lang, Deena Tajfirouz, Jessica A. Kraker et al.
Journal of Neuro-Ophthalmology
Cerebral Venous Sinus Thrombosis
article

Frequency of Nonspecific Optic Nerve Sheath Enhancement on Magnetic Resonance Imaging

Ajay A. Madhavan, Mary V. Lang, Deena Tajfirouz, Jessica A. Kraker, Kevin D. Chodnicki, John J. Chen, F. Paul
article en

Abstract

ONSE can be seen in a small proportion of patients without optic nerve pathology and may be missed in subtle disease, emphasizing the importance of clinical correlation. Higher field strength MRI may improve sensitivity for detecting pathologic ONSE but can have false positives. These findings underscore the need for cautious interpretation of ONSE, particularly in asymptomatic individuals or in the context of high-resolution imaging.

Journal of Neuro-Ophthalmology
Mayo Clinic (US), Mayo Clinic in Florida (US)
Openalex Percentile: Top 44%
Cerebral Venous Sinus Thrombosis
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