Association of Podometric Parameters with the Oxford MEST-C Score and Pre-Treatment eGFR Slope in Patients with IgA Nephropathy

The podocyte number at the time of kidney biopsy was associated with the pre-biopsy estimated glomerular filtration rate decline slope in patients with immunoglobulin A nephropathy. Furthermore, elevated urinary podocyte mRNA levels suggested the presence of E and C lesions. Podometrics may serve as a potentially less invasive marker for monitoring disease activity and guiding treatment strategies.

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Publication Details

Journal
Kidney360
Published
2025-12-18
DOI
https://doi.org/10.34067/kid.0000001095
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of Podometric Parameters with the Oxford MEST-C Score and Pre-Treatment eGFR Slope in Patients with IgA Nephropathy

Shouichi Fujimoto, Shoko Ochiai, Koichi Kaikita, M Kikuchi
Kidney360
Renal Diseases and Glomerulopathies
article

Association of Podometric Parameters with the Oxford MEST-C Score and Pre-Treatment eGFR Slope in Patients with IgA Nephropathy

Shouichi Fujimoto, Shoko Ochiai, Koichi Kaikita, M Kikuchi
article en

Abstract

The podocyte number at the time of kidney biopsy was associated with the pre-biopsy estimated glomerular filtration rate decline slope in patients with immunoglobulin A nephropathy. Furthermore, elevated urinary podocyte mRNA levels suggested the presence of E and C lesions. Podometrics may serve as a potentially less invasive marker for monitoring disease activity and guiding treatment strategies.

Kidney360
University of Miyazaki (JP)
Openalex Percentile: Top 49%
Renal Diseases and Glomerulopathies
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