PRSS22 promotes the immune evasion of gastric cancer via inhibiting ANXA1-mediated degradation of PD-1
PRSS22 suppressed ANXA1-mediated degradation of PD-1 in T cell to promote the immune evasion of GC. Targeting PRSS22 is thus a potentially effective therapeutic strategy for GC.
Authors
- Jifan Wang (ORCID: https://orcid.org/0000-0001-9720-8913)
- Xiaoping Chen (ORCID: https://orcid.org/0000-0003-3166-6625)
- Jing Zhou (ORCID: https://orcid.org/0009-0008-4231-1460)
Institutions
- Jiangnan University (CN)
Publication Details
- Journal
- Food & Nutrition Research
- Published
- 2025-12-18
- DOI
- https://doi.org/10.29219/fnr.v69.13155
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00