From manual to automated: building scalable workflows for autologous CAR-T cell manufacturing

Automation can enhance scalability, consistency, and efficiency in autologous CAR-T cell therapies, but adoption must be carefully phased and aligned with operational goals. This interactive poster illustrates how automation can overcome challenges in autologous CAR-T cell manufacturing, including patient variability, labor-intensive workflows, supply chain issues, and scalability, and includes soundbites from a panel of leading experts – Edwin Stone (CEO, Cellular Origins), Mojtaba Parvizi (Global Fast Trak Director, Cell Therapy, Cytiva), and Matthew Hewitt ( Vice President, CTO Manufacturing Division, Charles River Laboratories).

Authors

Publication Details

Journal
Cell and Gene Therapy Insights
Published
2025-12-18
DOI
https://doi.org/10.18609/cgti.2025.169
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

From manual to automated: building scalable workflows for autologous CAR-T cell manufacturing

Mahdi Parvizi, Matthew Hewitt, Edwin M. Stone
Cell and Gene Therapy Insights
CAR-T cell therapy research
article

From manual to automated: building scalable workflows for autologous CAR-T cell manufacturing

Mahdi Parvizi, Matthew Hewitt, Edwin M. Stone
article en

Abstract

Automation can enhance scalability, consistency, and efficiency in autologous CAR-T cell therapies, but adoption must be carefully phased and aligned with operational goals. This interactive poster illustrates how automation can overcome challenges in autologous CAR-T cell manufacturing, including patient variability, labor-intensive workflows, supply chain issues, and scalability, and includes soundbites from a panel of leading experts – Edwin Stone (CEO, Cellular Origins), Mojtaba Parvizi (Global Fast Trak Director, Cell Therapy, Cytiva), and Matthew Hewitt ( Vice President, CTO Manufacturing Division, Charles River Laboratories).

Cell and Gene Therapy InsightsVol. 11(11)
Openalex Percentile: Top 43%
CAR-T cell therapy research
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