From manual to automated: building scalable workflows for autologous CAR-T cell manufacturing
Automation can enhance scalability, consistency, and efficiency in autologous CAR-T cell therapies, but adoption must be carefully phased and aligned with operational goals. This interactive poster illustrates how automation can overcome challenges in autologous CAR-T cell manufacturing, including patient variability, labor-intensive workflows, supply chain issues, and scalability, and includes soundbites from a panel of leading experts – Edwin Stone (CEO, Cellular Origins), Mojtaba Parvizi (Global Fast Trak Director, Cell Therapy, Cytiva), and Matthew Hewitt ( Vice President, CTO Manufacturing Division, Charles River Laboratories).
Authors
- Mahdi Parvizi (ORCID: https://orcid.org/0000-0003-4848-9469)
- Matthew Hewitt (ORCID: https://orcid.org/0000-0001-8915-1996)
- Edwin M. Stone (ORCID: https://orcid.org/0000-0003-3343-4414)
Publication Details
- Journal
- Cell and Gene Therapy Insights
- Published
- 2025-12-18
- DOI
- https://doi.org/10.18609/cgti.2025.169
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00