A Machine Learning Approach to Predicting Mortality Risk in Chemotherapy-Treated Lung Cancer: Machine Learning Model Development and Validation
Our ML models exhibited acceptable discrimination, calibration, and clinical benefit in predicting the mortality risk of chemotherapy-treated patients with lung cancer, which could help clinicians in personalized prognostic management.
Authors
- Jiachun Lü (ORCID: https://orcid.org/0000-0002-6189-826X)
- Ao Lin (ORCID: https://orcid.org/0000-0001-7817-1617)
- Katie Lu (ORCID: https://orcid.org/0009-0000-8588-2505)
- J Y Zhang (ORCID: https://orcid.org/0009-0004-4956-1404)
- Fuman Qiu (ORCID: https://orcid.org/0000-0003-2882-6413)
- Xin Zhang
- Zhi Li (ORCID: https://orcid.org/0009-0008-1277-7796)
- Ling Lu (ORCID: https://orcid.org/0009-0003-9244-015X)
- Jinbin Chen (ORCID: https://orcid.org/0009-0001-6617-4471)
- Lei Yang (ORCID: https://orcid.org/0000-0002-1315-7651)
- Dongming Xie (ORCID: https://orcid.org/0009-0007-6935-6709)
- Yibin Deng (ORCID: https://orcid.org/0000-0002-0869-0400)
- Jianjun Zou (ORCID: https://orcid.org/0000-0001-6274-5778)
- Feng Luo (ORCID: https://orcid.org/0009-0006-9343-0721)
- Xie Chen (ORCID: https://orcid.org/0009-0000-1693-9993)
- Boqi Rao (ORCID: https://orcid.org/0000-0002-9093-8064)
- Jinyi Huang
Institutions
- University of Arizona (US)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Center for Tuberculosis Control of Guangdong Province (CN)
- Kingmed Diagnostics (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- State Key Laboratory of Respiratory Disease (CN)
- Guangzhou Chest Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- JMIR Medical Informatics
- Published
- 2025-12-18
- DOI
- https://doi.org/10.2196/72424
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00