Three-dimensional bioprinting of patient-derived Gastrointestinal stromal tumor: a novel platform for precision oncology and drug response profiling
Overall, the 3DP-GIST model represents a robust and efficient platform for evaluating patient-specific drug sensitivities in vitro, thereby guiding personalized therapeutic strategies for GIST patients.
Authors
- Yan Lü (ORCID: https://orcid.org/0000-0003-3468-2241)
- Liwei Du (ORCID: https://orcid.org/0000-0002-7706-5967)
- Mingchang Pang
- Yanni He (ORCID: https://orcid.org/0000-0002-8323-2979)
- Shangze Jiang
- Weiming Kang (ORCID: https://orcid.org/0000-0002-6736-4728)
- Shunda Du (ORCID: https://orcid.org/0000-0002-9357-3259)
- Zicheng Zheng (ORCID: https://orcid.org/0000-0002-0984-5849)
- Yanan Wang (ORCID: https://orcid.org/0000-0003-1900-8400)
- Huayu Yang (ORCID: https://orcid.org/0000-0001-9791-3559)
- Yilei Mao (ORCID: https://orcid.org/0000-0003-0449-4223)
- Kai Zhang (ORCID: https://orcid.org/0000-0002-7877-4538)
- Haitao Zhao (ORCID: https://orcid.org/0000-0002-4728-0180)
- Minghao Sun (ORCID: https://orcid.org/0000-0002-1657-0740)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1186/s12951-025-03934-6
- Primary Topic
- Gastrointestinal Tumor Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Peking Union Medical College Hospital
- National Science and Technology Major Project