TRIM2 exacerbates the advancement of idiopathic pulmonary fibrosis by modulating β-catenin and endoplasmic reticulum stress
This study demonstrates that TRIM2 promotes idiopathic pulmonary fibrosis progression by regulating β-catenin expression and endoplasmic reticulum stress, providing new insights into IPF pathogenesis.
Authors
- Yong Zhang (ORCID: https://orcid.org/0000-0003-3704-4835)
- Jie Ling (ORCID: https://orcid.org/0000-0001-7054-5119)
- Ganjuan Nie
- Di Jiang (ORCID: https://orcid.org/0000-0001-9795-6831)
- Mi Tang (ORCID: https://orcid.org/0009-0006-6548-8694)
- Z Lei (ORCID: https://orcid.org/0009-0008-3692-5466)
- Yuelin Hu (ORCID: https://orcid.org/0000-0003-3466-748X)
- Hengzhong Yi
Institutions
- Hunan Province Chest Hospital (CN)
- First Affiliated Hospital of University of South China (CN)
- University of South China (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1186/s40001-025-03642-9
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00