Comment to: Vegetable peptones as a fetal bovine serum substitute in human deciduous tooth pulp stem cell culture

Dear Editor, The innovative use of vegetable peptones as substitutes for fetal bovine serum (FBS) in stem cell culture presents promising advantages. Replacing FBS addresses major ethical and biosafety concerns, reduces batch variability, and lowers the risk of xenogeneic contamination – factors crucial for translational and clinical cell therapies. Notably, wheat peptone supported equal or superior cell proliferation and osteogenic differentiation than that of FBS, likely because of its high glutamic acid and proline content. […] Comment to: Vegetable peptones [...]

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Publication Details

Journal
Einstein (São Paulo)
Published
2025-12-17
DOI
https://doi.org/10.31744/einstein_journal/2026ce2068
Primary Topic
Pluripotent Stem Cells Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Comment to: Vegetable peptones as a fetal bovine serum substitute in human deciduous tooth pulp stem cell culture

Nareshwaran Gnanasegaran
Einstein (São Paulo)
Pluripotent Stem Cells Research
article

Comment to: Vegetable peptones as a fetal bovine serum substitute in human deciduous tooth pulp stem cell culture

Nareshwaran Gnanasegaran
article en

Abstract

Dear Editor, The innovative use of vegetable peptones as substitutes for fetal bovine serum (FBS) in stem cell culture presents promising advantages. Replacing FBS addresses major ethical and biosafety concerns, reduces batch variability, and lowers the risk of xenogeneic contamination – factors crucial for translational and clinical cell therapies. Notably, wheat peptone supported equal or superior cell proliferation and osteogenic differentiation than that of FBS, likely because of its high glutamic acid and proline content. […] Comment to: Vegetable peptones [...]

Einstein (São Paulo)Vol. 24
Merck (Singapore) (SG)
Openalex Percentile: Top 63%
Pluripotent Stem Cells Research
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