Long-term considerations following living liver donation—Guidelines from the 2025 ILTS-iLDLT consensus conference on living liver donor safety
Living liver donation is a critical component for addressing organ shortage and improving outcomes for patients with end-stage liver disease. As the prevalence of living donor liver transplantation (LDLT) increases worldwide, understanding and optimizing long-term donor health is paramount. The 2025 International Liver Transplantation Society and International Living Donor Liver Transplantation Society (ILTS-iLDLT) Consensus Conference convened experts in the field of liver transplantation to establish evidence-based guidelines focused on the long-term medical, psychological, and social considerations following living liver donation. The aim of this working group was to integrate current evidence and expert consensus on donor follow-up protocols, risk assessment, and management strategies to promote long-term donor health, quality of life, and living liver donor programs globally to safeguard the welfare of this unique population.
Authors
- Johns Shaji Mathew (ORCID: https://orcid.org/0000-0003-1590-999X)
- Albert Chan (ORCID: https://orcid.org/0000-0002-1383-2952)
- Julie K. Heimbach (ORCID: https://orcid.org/0000-0002-3567-1328)
- Zhi‐Jun Zhu (ORCID: https://orcid.org/0000-0001-7031-2083)
- Dieter Broering (ORCID: https://orcid.org/0000-0003-0422-0409)
- Prashant Bhangui (ORCID: https://orcid.org/0000-0002-4839-5852)
- John P. Roberts (ORCID: https://orcid.org/0000-0003-3303-9406)
- Ashwin Rammohan (ORCID: https://orcid.org/0000-0001-9528-8892)
- Norah A. Terrault (ORCID: https://orcid.org/0000-0003-4143-1950)
- Daniel G. Maluf (ORCID: https://orcid.org/0000-0002-5921-4834)
- Patrizia Burra (ORCID: https://orcid.org/0000-0002-8791-191X)
- Blayne Amir Sayed (ORCID: https://orcid.org/0000-0003-3224-8871)
- Gideon M. Hirschfield (ORCID: https://orcid.org/0000-0002-6736-2255)
- Sudha Kodali (ORCID: https://orcid.org/0000-0002-2816-9647)
- Susumu Eguchi (ORCID: https://orcid.org/0000-0002-7876-0152)
- Nicholas Syn (ORCID: https://orcid.org/0000-0002-6343-176X)
- Nicolás Goldaracena (ORCID: https://orcid.org/0000-0002-6623-5561)
- Nazia Selzner (ORCID: https://orcid.org/0000-0002-9435-2597)
- Timuçin Taner (ORCID: https://orcid.org/0000-0003-0641-2930)
- Mary Vyas
- Kim M. Olthoff (ORCID: https://orcid.org/0000-0001-5181-7502)
- Elizabeth A. Pomfret (ORCID: https://orcid.org/0000-0001-7970-1325)
- Kymberly D. Watt (ORCID: https://orcid.org/0000-0003-0828-0644)
- Nancy Kwan Man
- Sadhana Shankar (ORCID: https://orcid.org/0000-0001-5802-2403)
- Charles L. Wiggins (ORCID: https://orcid.org/0000-0002-0661-8261)
- Robert C. Minnee (ORCID: https://orcid.org/0000-0002-9494-3717)
- David C. Fipps (ORCID: https://orcid.org/0000-0001-5758-704X)
- Nancy L. Ascher (ORCID: https://orcid.org/0000-0002-7039-4514)
- Paul M. James
- Markus Selzner (ORCID: https://orcid.org/0000-0002-4326-0887)
- AnnMarie Liapakis (ORCID: https://orcid.org/0000-0003-4484-6190)
- Bijan Eghtesad (ORCID: https://orcid.org/0000-0002-7857-0092)
- Jan Lerut (ORCID: https://orcid.org/0000-0003-4015-463X)
- Abhideep Chaudhary (ORCID: https://orcid.org/0000-0003-4817-4336)
- Jong Man Kim (ORCID: https://orcid.org/0000-0002-1903-8354)
- Mohamed Rela
- Dong-Hwan Jung
- Chao‐Long Chen
- Valeria Mas
- Kyung Suk-Suh
Institutions
- Ulsan College (KR)
- University of Southern California (US)
- University of Maryland, Baltimore (US)
- Medanta The Medicity (IN)
- Houston Methodist (US)
- University of Maryland Medical Center (US)
- Cleveland Clinic (US)
- University Health Network (CA)
- Mayo Clinic (US)
- University of Padua (IT)
- Seoul National University (KR)
- National University of Singapore (SG)
- University of Toronto (CA)
- University of Virginia Health System (US)
- Hospital of the University of Pennsylvania (US)
- King Faisal Specialist Hospital & Research Centre (SA)
- Hospital for Sick Children (CA)
- Asan Medical Center (KR)
- Toronto General Hospital (CA)
- Erasmus MC (NL)
- Samsung Medical Center (KR)
- WinnMed (US)
- Max Super Speciality Hospital (IN)
- University of Ulsan (KR)
- NYU Langone Health (US)
- Technology Innovation Institute (AE)
- National Clinical Research Center for Digestive Diseases (CN)
- Kaohsiung Chang Gung Memorial Hospital (TW)
- Sheikh Shakhbout Medical City (AE)
- Mohamed I University (MA)
- Methodist Hospital (US)
- University of California San Francisco Medical Center (US)
- Medanta The Medicity (IN)
- BLK Super Speciality Hospital (IN)
- Mayo Clinic in Arizona (US)
- Erasmus MC Cancer Institute (NL)
- Miami Transplant Institute (US)
- PSC Partners Seeking a Cure (US)
- Nagasaki University (JP)
- University of Colorado Anschutz Medical Campus (US)
- Sungkyunkwan University (KR)
- Bharath University (IN)
- University of Hong Kong (HK)
- UCLouvain (BE)
Publication Details
- Journal
- Liver Transplantation
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1097/lvt.0000000000000790
- Citations
- 2
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.01